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New insights into posttranslational modifications of Hippo pathway in carcinogenesis and therapeutics

PTMs (posttranslational modifications) such as ubiquitylation, sumoylation, acetylation and protein methylation are pivotal modifiers that determine the activation, deactivation or subcellular localization of signaling proteins, facilitating the initiation, amplification and transduction of signalin...

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Detalles Bibliográficos
Autores principales: He, Mingjing, Zhou, Zhuan, Shah, Anil A., Hong, Yang, Chen, Qianming, Wan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818516/
https://www.ncbi.nlm.nih.gov/pubmed/27042197
http://dx.doi.org/10.1186/s13008-016-0013-6