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Detection and monitoring of hypermethylated RASSF1A in serum from patients with metastatic breast cancer

BACKGROUND: Circulating hypermethylated RASSF1A could be a novel and potential useful marker for monitoring patients with metastatic breast cancer. Technical obstacles include fragmentation of the circulating DNA, fluctuations in the concentration, low concentrations of circulating tumor DNA, and di...

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Detalles Bibliográficos
Autores principales: Kristiansen, Søren, Nielsen, Dorte, Sölétormos, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818536/
https://www.ncbi.nlm.nih.gov/pubmed/27042241
http://dx.doi.org/10.1186/s13148-016-0199-0