Lactation opposes pappalysin‐1‐driven pregnancy‐associated breast cancer

Pregnancy is associated with a transient increase in risk for breast cancer. However, the mechanism underlying pregnancy‐associated breast cancer (PABC) is poorly understood. Here, we identify the protease pappalysin‐1 (PAPP‐A) as a pregnancy‐dependent oncogene. Transgenic expression of PAPP‐A in th...

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Detalles Bibliográficos
Autores principales: Takabatake, Yukie, Oxvig, Claus, Nagi, Chandandeep, Adelson, Kerin, Jaffer, Shabnam, Schmidt, Hank, Keely, Patricia J, Eliceiri, Kevin W, Mandeli, John, Germain, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818749/
https://www.ncbi.nlm.nih.gov/pubmed/26951623
http://dx.doi.org/10.15252/emmm.201606273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818749/
https://www.ncbi.nlm.nih.gov/pubmed/26951623
http://dx.doi.org/10.15252/emmm.201606273

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