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Lactation opposes pappalysin‐1‐driven pregnancy‐associated breast cancer

Pregnancy is associated with a transient increase in risk for breast cancer. However, the mechanism underlying pregnancy‐associated breast cancer (PABC) is poorly understood. Here, we identify the protease pappalysin‐1 (PAPP‐A) as a pregnancy‐dependent oncogene. Transgenic expression of PAPP‐A in th...

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Detalles Bibliográficos
Autores principales:	Takabatake, Yukie, Oxvig, Claus, Nagi, Chandandeep, Adelson, Kerin, Jaffer, Shabnam, Schmidt, Hank, Keely, Patricia J, Eliceiri, Kevin W, Mandeli, John, Germain, Doris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818749/ https://www.ncbi.nlm.nih.gov/pubmed/26951623 http://dx.doi.org/10.15252/emmm.201606273

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