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Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense oligonucleotides

Apolipoprotein E receptor 2 (ApoER2) is an apolipoprotein E receptor involved in long‐term potentiation, learning, and memory. Given its role in cognition and its association with the Alzheimer's disease (AD) risk gene, apoE, ApoER2 has been proposed to be involved in AD, though a role for the...

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Detalles Bibliográficos
Autores principales: Hinrich, Anthony J, Jodelka, Francine M, Chang, Jennifer L, Brutman, Daniella, Bruno, Angela M, Briggs, Clark A, James, Bryan D, Stutzmann, Grace E, Bennett, David A, Miller, Steven A, Rigo, Frank, Marr, Robert A, Hastings, Michelle L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818756/
https://www.ncbi.nlm.nih.gov/pubmed/26902204
http://dx.doi.org/10.15252/emmm.201505846