miR‐515‐5p controls cancer cell migration through MARK4 regulation

Here, we show that miR‐515‐5p inhibits cancer cell migration and metastasis. RNA‐seq analyses of both oestrogen receptor receptor‐positive and receptor‐negative breast cancer cells overexpressing miR‐515‐5p reveal down‐regulation of NRAS, FZD4, CDC42BPA, PIK3C2B and MARK4 mRNAs. We demonstrate that...

Descripción completa

Detalles Bibliográficos
Autores principales: Pardo, Olivier E, Castellano, Leandro, Munro, Catriona E, Hu, Yili, Mauri, Francesco, Krell, Jonathan, Lara, Romain, Pinho, Filipa G, Choudhury, Thameenah, Frampton, Adam E, Pellegrino, Loredana, Pshezhetskiy, Dmitry, Wang, Yulan, Waxman, Jonathan, Seckl, Michael J, Stebbing, Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818771/
https://www.ncbi.nlm.nih.gov/pubmed/26882547
http://dx.doi.org/10.15252/embr.201540970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818771/
https://www.ncbi.nlm.nih.gov/pubmed/26882547
http://dx.doi.org/10.15252/embr.201540970

Ejemplares similares