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Centromere localization and function of Mis18 requires Yippee‐like domain‐mediated oligomerization

Mis18 is a key regulator responsible for the centromere localization of the CENP‐A chaperone Scm3 in Schizosaccharomyces pombe and HJURP in humans, which establishes CENP‐A chromatin that defines centromeres. The molecular and structural determinants of Mis18 centromere targeting remain elusive. Her...

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Detalles Bibliográficos
Autores principales: Subramanian, Lakxmi, Medina‐Pritchard, Bethan, Barton, Rachael, Spiller, Frances, Kulasegaran‐Shylini, Raghavendran, Radaviciute, Guoda, Allshire, Robin C, Arockia Jeyaprakash, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818781/
https://www.ncbi.nlm.nih.gov/pubmed/26921242
http://dx.doi.org/10.15252/embr.201541520