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Autophagy induction by SIRT6 is involved in oxidative stress-induced neuronal damage

SIRT6 is a NAD(+)-dependent histone deacetylase and has been implicated in the regulation of genomic stability, DNA repair, metabolic homeostasis and several diseases. The effect of SIRT6 in cerebral ischemia and oxygen/glucose deprivation (OGD) has been reported, however the role of SIRT6 in oxidat...

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Detalles Bibliográficos
Autores principales: Shao, Jiaxiang, Yang, Xiao, Liu, Tengyuan, Zhang, Tingting, Xie, Qian Reuben, Xia, Weiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818841/
https://www.ncbi.nlm.nih.gov/pubmed/26983852
http://dx.doi.org/10.1007/s13238-016-0257-6