Evolutionary triangulation: informing genetic association studies with evolutionary evidence

Genetic studies of human diseases have identified many variants associated with pathogenesis and severity. However, most studies have used only statistical association to assess putative relationships to disease, and ignored other factors for evaluation. For example, evolution is a factor that has s...

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Detalles Bibliográficos
Autores principales: Huang, Minjun, Graham, Britney E., Zhang, Ge, Harder, Reed, Kodaman, Nuri, Moore, Jason H., Muglia, Louis, Williams, Scott M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818851/
https://www.ncbi.nlm.nih.gov/pubmed/27042214
http://dx.doi.org/10.1186/s13040-016-0091-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818851/
https://www.ncbi.nlm.nih.gov/pubmed/27042214
http://dx.doi.org/10.1186/s13040-016-0091-7

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