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Evolutionary triangulation: informing genetic association studies with evolutionary evidence
Genetic studies of human diseases have identified many variants associated with pathogenesis and severity. However, most studies have used only statistical association to assess putative relationships to disease, and ignored other factors for evaluation. For example, evolution is a factor that has s...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818851/ https://www.ncbi.nlm.nih.gov/pubmed/27042214 http://dx.doi.org/10.1186/s13040-016-0091-7 |