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Pioglitazone ameliorates the phenotype of a novel Parkinson’s disease mouse model by reducing neuroinflammation

BACKGROUND: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by motor and non-motor symptoms. The cause of the motor symptoms is the loss of dopaminergic neurons in the substantia nigra with consequent depletion of dopamine in the striatum. Although the etiology of...

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Detalles Bibliográficos
Autores principales: Pinto, Milena, Nissanka, Nadee, Peralta, Susana, Brambilla, Roberta, Diaz, Francisca, Moraes, Carlos T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818913/
https://www.ncbi.nlm.nih.gov/pubmed/27038906
http://dx.doi.org/10.1186/s13024-016-0090-7