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Pioglitazone ameliorates the phenotype of a novel Parkinson’s disease mouse model by reducing neuroinflammation
BACKGROUND: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by motor and non-motor symptoms. The cause of the motor symptoms is the loss of dopaminergic neurons in the substantia nigra with consequent depletion of dopamine in the striatum. Although the etiology of...
Autores principales: | Pinto, Milena, Nissanka, Nadee, Peralta, Susana, Brambilla, Roberta, Diaz, Francisca, Moraes, Carlos T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818913/ https://www.ncbi.nlm.nih.gov/pubmed/27038906 http://dx.doi.org/10.1186/s13024-016-0090-7 |
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