GWAS and transcriptional analysis prioritize ITPR1 and CNTN4 for a serum uric acid 3p26 QTL in Mexican Americans

BACKGROUND: The variation in serum uric acid concentrations is under significant genetic influence. Elevated SUA concentrations have been linked to increased risk for gout, kidney stones, chronic kidney disease, and cardiovascular disease whereas reduced serum uric acid concentrations have been link...

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Detalles Bibliográficos
Autores principales: Chittoor, Geetha, Kent, Jack W., Almeida, Marcio, Puppala, Sobha, Farook, Vidya S., Cole, Shelley A., Haack, Karin, Göring, Harald H. H., MacCluer, Jean W., Curran, Joanne E., Carless, Melanie A., Johnson, Matthew P., Moses, Eric K., Almasy, Laura, Mahaney, Michael C., Lehman, Donna M., Duggirala, Ravindranath, Comuzzie, Anthony G., Blangero, John, Voruganti, Venkata Saroja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818944/
https://www.ncbi.nlm.nih.gov/pubmed/27039371
http://dx.doi.org/10.1186/s12864-016-2594-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818944/
https://www.ncbi.nlm.nih.gov/pubmed/27039371
http://dx.doi.org/10.1186/s12864-016-2594-5

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