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A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons

Notch signaling plays crucial roles for cellular differentiation during development through γ-secretase-dependent intramembrane proteolysis followed by transcription of target genes. Although recent studies implicate that Notch regulates synaptic plasticity or cognitive performance, the molecular me...

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Detalles Bibliográficos
Autores principales: Hayashi, Yukari, Nishimune, Hiroshi, Hozumi, Katsuto, Saga, Yumiko, Harada, Akihiro, Yuzaki, Michisuke, Iwatsubo, Takeshi, Kopan, Raphael, Tomita, Taisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819173/
https://www.ncbi.nlm.nih.gov/pubmed/27040987
http://dx.doi.org/10.1038/srep23969