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Glucocorticoids impair oocyte developmental potential by triggering apoptosis of ovarian cells via activating the Fas system

Previous studies indicate that stress damages oocytes with increased secretion of glucorticoids. However, although injection of female mice with cortisol decreased oocyte competence, exposure of mouse oocytes directly to physiological or stress-induced concentrations of glucorticoids did not affect...

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Detalles Bibliográficos
Autores principales: Yuan, Hong-Jie, Han, Xiao, He, Nan, Wang, Guo-Liang, Gong, Shuai, Lin, Juan, Gao, Min, Tan, Jing-He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819190/
https://www.ncbi.nlm.nih.gov/pubmed/27040909
http://dx.doi.org/10.1038/srep24036