Tracking of Normal and Malignant Progenitor Cell Cycle Transit in a Defined Niche

While implicated in therapeutic resistance, malignant progenitor cell cycle kinetics have been difficult to quantify in real-time. We developed an efficient lentiviral bicistronic fluorescent, ubiquitination-based cell cycle indicator reporter (Fucci2BL) to image live single progenitors on a defined...

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Detalles Bibliográficos
Autores principales: Pineda, Gabriel, Lennon, Kathleen M., Delos Santos, Nathaniel P., Lambert-Fliszar, Florence, Riso, Gennarina L., Lazzari, Elisa, Marra, Marco A., Morris, Sheldon, Sakaue-Sawano, Asako, Miyawaki, Atsushi, Jamieson, Catriona H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819192/
https://www.ncbi.nlm.nih.gov/pubmed/27041210
http://dx.doi.org/10.1038/srep23885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819192/
https://www.ncbi.nlm.nih.gov/pubmed/27041210
http://dx.doi.org/10.1038/srep23885

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