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Tracking of Normal and Malignant Progenitor Cell Cycle Transit in a Defined Niche
While implicated in therapeutic resistance, malignant progenitor cell cycle kinetics have been difficult to quantify in real-time. We developed an efficient lentiviral bicistronic fluorescent, ubiquitination-based cell cycle indicator reporter (Fucci2BL) to image live single progenitors on a defined...
Autores principales: | Pineda, Gabriel, Lennon, Kathleen M., Delos Santos, Nathaniel P., Lambert-Fliszar, Florence, Riso, Gennarina L., Lazzari, Elisa, Marra, Marco A., Morris, Sheldon, Sakaue-Sawano, Asako, Miyawaki, Atsushi, Jamieson, Catriona H. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819192/ https://www.ncbi.nlm.nih.gov/pubmed/27041210 http://dx.doi.org/10.1038/srep23885 |
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