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Conditional Deletion of Fgfr3 in Chondrocytes leads to Osteoarthritis-like Defects in Temporomandibular Joint of Adult Mice

Osteoarthritis (OA) in the temporomandibular joint (TMJ) is a common degenerative disease in adult, which is characterized by progressive destruction of the articular cartilage. To investigate the role of FGFR3 in the homeostasis of TMJ cartilage during adult stage, we generated Fgfr3(f/f); Col2a1-C...

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Detalles Bibliográficos
Autores principales: Zhou, Siru, Xie, Yangli, Li, Wei, Huang, Junlan, Wang, Zuqiang, Tang, Junzhou, Xu, Wei, Sun, Xianding, Tan, Qiaoyan, Huang, Shuo, Luo, Fengtao, Xu, Meng, Wang, Jun, Wu, Tingting, chen, Liang, Chen, Hangang, Su, Nan, Du, Xiaolan, Shen, Yue, Chen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819201/
https://www.ncbi.nlm.nih.gov/pubmed/27041063
http://dx.doi.org/10.1038/srep24039