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Conditional Deletion of Fgfr3 in Chondrocytes leads to Osteoarthritis-like Defects in Temporomandibular Joint of Adult Mice
Osteoarthritis (OA) in the temporomandibular joint (TMJ) is a common degenerative disease in adult, which is characterized by progressive destruction of the articular cartilage. To investigate the role of FGFR3 in the homeostasis of TMJ cartilage during adult stage, we generated Fgfr3(f/f); Col2a1-C...
Autores principales: | Zhou, Siru, Xie, Yangli, Li, Wei, Huang, Junlan, Wang, Zuqiang, Tang, Junzhou, Xu, Wei, Sun, Xianding, Tan, Qiaoyan, Huang, Shuo, Luo, Fengtao, Xu, Meng, Wang, Jun, Wu, Tingting, chen, Liang, Chen, Hangang, Su, Nan, Du, Xiaolan, Shen, Yue, Chen, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819201/ https://www.ncbi.nlm.nih.gov/pubmed/27041063 http://dx.doi.org/10.1038/srep24039 |
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