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Some pitfalls in application of functional data analysis approach to association studies

One of the most effective methods for gene-based mapping employs functional data analysis, which smoothes data using standard basis functions. The full functional linear model includes a functional representation of genotypes and their effects, while the beta-smooth only model smoothes the genotype...

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Detalles Bibliográficos
Autores principales: Svishcheva, G. R., Belonogova, N. M., Axenovich, T. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819216/
https://www.ncbi.nlm.nih.gov/pubmed/27041739
http://dx.doi.org/10.1038/srep23918