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Some pitfalls in application of functional data analysis approach to association studies
One of the most effective methods for gene-based mapping employs functional data analysis, which smoothes data using standard basis functions. The full functional linear model includes a functional representation of genotypes and their effects, while the beta-smooth only model smoothes the genotype...
Autores principales: | Svishcheva, G. R., Belonogova, N. M., Axenovich, T. I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819216/ https://www.ncbi.nlm.nih.gov/pubmed/27041739 http://dx.doi.org/10.1038/srep23918 |
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