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Novel PKC-ζ to p47(phox) interaction is necessary for transformation from blebbishields

Cancer stem cells are capable of transformation after apoptosis through the blebbishield emergency program. Reactive oxygen species (ROS) play an essential role in transformation. Understanding how ROS are linked to blebbishield-mediated transformation is necessary to develop efficient therapeutics...

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Detalles Bibliográficos
Autores principales: Jinesh, Goodwin G., Taoka, Rikiya, Zhang, Qiang, Gorantla, Siddharth, Kamat, Ashish M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819220/
https://www.ncbi.nlm.nih.gov/pubmed/27040869
http://dx.doi.org/10.1038/srep23965