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New Hippocampal Neurons Mature Rapidly in Response to Ketamine But Are Not Required for Its Acute Antidepressant Effects on Neophagia in Rats123

Virtually all antidepressant agents increase the birth of granule neurons in the adult dentate gyrus in rodents, providing a key basis for the neurogenesis hypothesis of antidepressant action. The novel antidepressant ketamine, however, shows antidepressant activity in humans within hours, far too r...

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Detalles Bibliográficos
Autores principales: Soumier, Amelie, Carter, Rayna M., Schoenfeld, Timothy J., Cameron, Heather A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819285/
https://www.ncbi.nlm.nih.gov/pubmed/27066531
http://dx.doi.org/10.1523/ENEURO.0116-15.2016