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New Hippocampal Neurons Mature Rapidly in Response to Ketamine But Are Not Required for Its Acute Antidepressant Effects on Neophagia in Rats123
Virtually all antidepressant agents increase the birth of granule neurons in the adult dentate gyrus in rodents, providing a key basis for the neurogenesis hypothesis of antidepressant action. The novel antidepressant ketamine, however, shows antidepressant activity in humans within hours, far too r...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819285/ https://www.ncbi.nlm.nih.gov/pubmed/27066531 http://dx.doi.org/10.1523/ENEURO.0116-15.2016 |