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Differential Expression of OCT4 Pseudogenes in Pluripotent and Tumor Cell Lines

OBJECTIVE: The human OCT4 gene, the most important pluripotency marker, can generate at least three different transcripts (OCT4A, OCT4B, and OCT4B1) by alternative splicing. OCT4A is the main isoform responsible for the stemness property of embryonic stem (ES) cells. There also exist eight processed...

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Detalles Bibliográficos
Autores principales: Poursani, Ensieh M., Mohammad Soltani, Bahram, Mowla, Seyed Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819383/
https://www.ncbi.nlm.nih.gov/pubmed/27054116