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The natural compound chebulagic acid inhibits vascular endothelial growth factor A mediated regulation of endothelial cell functions
Vascular endothelial growth factor A (VEGFA) plays an important role in tumour angiogenesis and its angiogenic action is mainly mediated through its VEGF receptor 2 (VEGFR-2). Therefore drugs targeting VEGFA/VEGFR-2 are being presently used in the clinics for treatment of several types of solid mali...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819393/ https://www.ncbi.nlm.nih.gov/pubmed/25859636 http://dx.doi.org/10.1038/srep09642 |