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Metagenomic Sequencing with Strain-Level Resolution Implicates Uropathogenic E. coli in Necrotizing Enterocolitis and Mortality in Preterm Infants

Necrotizing enterocolitis (NEC) afflicts approximately 10% of extremely preterm infants with high fatality. Inappropriate bacterial colonization with Enterobacteriaceae is implicated, but no specific pathogen has been identified. We identify uropathogenic E. coli (UPEC) colonization as a significant...

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Detalles Bibliográficos
Autores principales: Ward, Doyle V., Scholz, Matthias, Zolfo, Moreno, Taft, Diana H., Schibler, Kurt R., Tett, Adrian, Segata, Nicola, Morrow, Ardythe L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819403/
https://www.ncbi.nlm.nih.gov/pubmed/26997279
http://dx.doi.org/10.1016/j.celrep.2016.03.015