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Rescuing axons from degeneration does not affect retinal ganglion cell death

After a traumatic injury to the central nervous system, the distal stumps of axons undergo Wallerian degeneration (WD), an event that comprises cytoskeleton and myelin breakdown, astrocytic gliosis, and overexpression of proteins that inhibit axonal regrowth. By contrast, injured neuronal cell bodie...

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Detalles Bibliográficos
Autores principales: de Lima, S., Mietto, B.S., Paula, C., Muniz, T., Martinez, A.M.B., Gardino, P.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819409/
https://www.ncbi.nlm.nih.gov/pubmed/27007653
http://dx.doi.org/10.1590/1414-431X20155106