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Inactivation of the miR-183/96/182 Cluster Decreases the Severity of Pseudomonas aeruginosa-Induced Keratitis

PURPOSE: The microRNA-183/96/182 cluster (miR-183/96/182) plays important roles in sensory organs. Because the cornea is replete with sensory innervation, we hypothesized that miR-183/96/182 modulates the corneal response to bacterial infection through regulation of neuroimmune interactions. METHODS...

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Detalles Bibliográficos
Autores principales: Muraleedharan, Chithra K., McClellan, Sharon A., Barrett, Ronald P., Li, Cui, Montenegro, Daniel, Carion, Thomas, Berger, Elizabeth, Hazlett, Linda D., Xu, Shunbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819431/
https://www.ncbi.nlm.nih.gov/pubmed/27035623
http://dx.doi.org/10.1167/iovs.16-19134