Expression of the MOZ-TIF2 oncoprotein in mice represses senescence

The MOZ-TIF2 translocation, which fuses monocytic leukemia zinc finger protein (MOZ) histone acetyltransferase (HAT) with the nuclear co-activator TIF2, is associated with the development of acute myeloid leukemia. We recently found that in the absence of MOZ HAT activity, p16(INK4a) transcriptional...

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Detalles Bibliográficos
Autores principales: Largeot, Anne, Perez-Campo, Flor Maria, Marinopoulou, Elli, Lie-a-Ling, Michael, Kouskoff, Valerie, Lacaud, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Inc 2016
Materias:
Malignant Hematopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819447/
https://www.ncbi.nlm.nih.gov/pubmed/26854485
http://dx.doi.org/10.1016/j.exphem.2015.12.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819447/
https://www.ncbi.nlm.nih.gov/pubmed/26854485
http://dx.doi.org/10.1016/j.exphem.2015.12.006

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