Cargando…
Distinct Structural Pathways Coordinate the Activation of AMPA Receptor-Auxiliary Subunit Complexes
Neurotransmitter-gated ion channels adopt different gating modes to fine-tune signaling at central synapses. At glutamatergic synapses, high and low activity of AMPA receptors (AMPARs) is observed when pore-forming subunits coassemble with or without auxiliary subunits, respectively. Whether a commo...
Autores principales: | Dawe, G. Brent, Musgaard, Maria, Aurousseau, Mark R.P., Nayeem, Naushaba, Green, Tim, Biggin, Philip C., Bowie, Derek |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819453/ https://www.ncbi.nlm.nih.gov/pubmed/26924438 http://dx.doi.org/10.1016/j.neuron.2016.01.038 |
Ejemplares similares
-
Kainate receptor pore‐forming and auxiliary subunits regulate channel block by a novel mechanism
por: Brown, Patricia M. G. E., et al.
Publicado: (2016) -
Defining the structural relationship between kainate receptor deactivation and desensitization
por: Dawe, G. Brent, et al.
Publicado: (2013) -
Auxiliary Subunits: Shepherding AMPA Receptors to the Plasma Membrane
por: Haering, Simon C., et al.
Publicado: (2014) -
Screening for AMPA receptor auxiliary subunit specific modulators
por: Azumaya, Caleigh M., et al.
Publicado: (2017) -
C-Terminal Interactors of the AMPA Receptor Auxiliary Subunit Shisa9
por: Karataeva, Anna R., et al.
Publicado: (2014)