Transcription factor KLF6 upregulates expression of metalloprotease MMP14 and subsequent release of soluble endoglin during vascular injury

After endothelial injury, the transcription factor Krüppel-like factor 6 (KLF6) translocates into the cell nucleus to regulate a variety of target genes involved in angiogenesis, vascular repair and remodeling, including components of the membrane transforming growth factor beta (TGF-β) receptor com...

Descripción completa

Detalles Bibliográficos
Autores principales: Gallardo-Vara, Eunate, Blanco, Francisco J., Roqué, Mercè, Friedman, Scott L., Suzuki, Toru, Botella, Luisa M., Bernabeu, Carmelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819519/
https://www.ncbi.nlm.nih.gov/pubmed/26850053
http://dx.doi.org/10.1007/s10456-016-9495-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819519/
https://www.ncbi.nlm.nih.gov/pubmed/26850053
http://dx.doi.org/10.1007/s10456-016-9495-8

Ejemplares similares