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Transcription factor KLF6 upregulates expression of metalloprotease MMP14 and subsequent release of soluble endoglin during vascular injury
After endothelial injury, the transcription factor Krüppel-like factor 6 (KLF6) translocates into the cell nucleus to regulate a variety of target genes involved in angiogenesis, vascular repair and remodeling, including components of the membrane transforming growth factor beta (TGF-β) receptor com...
Autores principales: | Gallardo-Vara, Eunate, Blanco, Francisco J., Roqué, Mercè, Friedman, Scott L., Suzuki, Toru, Botella, Luisa M., Bernabeu, Carmelo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819519/ https://www.ncbi.nlm.nih.gov/pubmed/26850053 http://dx.doi.org/10.1007/s10456-016-9495-8 |
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