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Sox2-Deficient Müller Glia Disrupt the Structural and Functional Maturation of the Mammalian Retina

PURPOSE: Müller glia (MG), the principal glial cells of the vertebrate retina, display quiescent progenitor cell characteristics. They express key progenitor markers, including the high mobility group box transcription factor SOX2 and maintain a progenitor-like morphology. In the embryonic and matur...

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Detalles Bibliográficos
Autores principales: Bachleda, Amelia R., Pevny, Larysa H., Weiss, Ellen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819558/
https://www.ncbi.nlm.nih.gov/pubmed/27031842
http://dx.doi.org/10.1167/iovs.15-17994