Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss

OBJECTIVES: Rheumatoid arthritis (RA)-specific anti-citrullinated protein/peptide antibodies (ACPAs) appear before disease onset and are associated with bone destruction. We aimed to dissect the role of ACPAs in osteoclast (OC) activation and to identify key cellular mediators in this process. METHO...

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Detalles Bibliográficos
Autores principales: Krishnamurthy, Akilan, Joshua, Vijay, Haj Hensvold, Aase, Jin, Tao, Sun, Meng, Vivar, Nancy, Ytterberg, A Jimmy, Engström, Marianne, Fernandes-Cerqueira, Cátia, Amara, Khaled, Magnusson, Malin, Wigerblad, Gustaf, Kato, Jungo, Jiménez-Andrade, Juan Miguel, Tyson, Kerry, Rapecki, Stephen, Lundberg, Karin, Catrina, Sergiu-Bogdan, Jakobsson, Per-Johan, Svensson, Camilla, Malmström, Vivianne, Klareskog, Lars, Wähämaa, Heidi, Catrina, Anca I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819614/
https://www.ncbi.nlm.nih.gov/pubmed/26612338
http://dx.doi.org/10.1136/annrheumdis-2015-208093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819614/
https://www.ncbi.nlm.nih.gov/pubmed/26612338
http://dx.doi.org/10.1136/annrheumdis-2015-208093

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