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Graft Site Microenvironment Determines Dendritic Cell Trafficking Through the CCR7-CCL19/21 Axis

PURPOSE: The graft site microenvironment has a profound effect on alloimmunity and graft survival. We aimed to study the kinetics and phenotype of trafficking antigen-presenting cells (APC) to the draining lymph nodes (DLNs) in a mouse model of corneal transplantation, and to evaluate the homing mec...

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Detalles Bibliográficos
Autores principales: Hua, Jing, Stevenson, William, Dohlman, Thomas H., Inomata, Takenori, Tahvildari, Maryam, Calcagno, Narghes, Pirmadjid, Negar, Sadrai, Zahra, Chauhan, Sunil K., Dana, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819620/
https://www.ncbi.nlm.nih.gov/pubmed/27031839
http://dx.doi.org/10.1167/iovs.15-17551