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Mitochondrial content is central to nuclear gene expression: Profound implications for human health

We review a recent paper in Genome Research by Guantes et al. showing that nuclear gene expression is influenced by the bioenergetic status of the mitochondria. The amount of energy that mitochondria make available for gene expression varies considerably. It depends on: the energetic demands of the...

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Detalles Bibliográficos
Autores principales: Muir, Rebecca, Diot, Alan, Poulton, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819685/
https://www.ncbi.nlm.nih.gov/pubmed/26725055
http://dx.doi.org/10.1002/bies.201500105