Chromosome engineering in zygotes with CRISPR/Cas9

Deletions, duplications, and inversions of large genomic regions covering several genes are an important class of disease causing variants in humans. Modeling these structural variants in mice requires multistep processes in ES cells, which has limited their availability. Mutant mice containing smal...

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Detalles Bibliográficos
Autores principales: Boroviak, Katharina, Doe, Brendan, Banerjee, Ruby, Yang, Fengtang, Bradley, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819711/
https://www.ncbi.nlm.nih.gov/pubmed/26742453
http://dx.doi.org/10.1002/dvg.22915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819711/
https://www.ncbi.nlm.nih.gov/pubmed/26742453
http://dx.doi.org/10.1002/dvg.22915

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