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Mitotic History Reveals Distinct Stem Cell Populations and Their Contributions to Hematopoiesis

Homeostasis of short-lived blood cells is dependent on rapid proliferation of immature precursors. Using a conditional histone 2B-mCherry-labeling mouse model, we characterize hematopoietic stem cell (HSC) and progenitor proliferation dynamics in steady state and following several types of induced s...

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Detalles Bibliográficos
Autores principales: Säwén, Petter, Lang, Stefan, Mandal, Pankaj, Rossi, Derrick J., Soneji, Shamit, Bryder, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819906/
https://www.ncbi.nlm.nih.gov/pubmed/26997272
http://dx.doi.org/10.1016/j.celrep.2016.02.073