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Identification of a Bipotent Epithelial Progenitor Population in the Adult Thymus
Thymic epithelial cells (TECs) are critically required for T cell development, but the cellular mechanisms that maintain adult TECs are poorly understood. Here, we show that a previously unidentified subpopulation, EpCam(+)UEA1(−)Ly-51(+)PLET1(+)MHC class II(hi), which comprises <0.5% of adult TE...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819909/ https://www.ncbi.nlm.nih.gov/pubmed/26997270 http://dx.doi.org/10.1016/j.celrep.2016.02.080 |