Amblyomin-X induces ER stress, mitochondrial dysfunction, and caspase activation in human melanoma and pancreatic tumor cell

During the last two decades, new insights into proteasome function and its role in several human diseases made it a potential therapeutic target. In this context, Amblyomin-X is a Kunitz-type FXa inhibitor similar to endogenous tissue factor pathway inhibitor (TFPI) and is a novel proteasome inhibit...

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Detalles Bibliográficos
Autores principales: Morais, Katia L. P., Pacheco, Mario Thiego Fernandes, Berra, Carolina Maria, Bosch, Rosemary V., Sciani, Juliana Mozer, Chammas, Roger, de Freitas Saito, Renata, Iqbal, Asif, Chudzinski-Tavassi, Ana Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819916/
https://www.ncbi.nlm.nih.gov/pubmed/27015684
http://dx.doi.org/10.1007/s11010-016-2683-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819916/
https://www.ncbi.nlm.nih.gov/pubmed/27015684
http://dx.doi.org/10.1007/s11010-016-2683-4

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