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Xenopus LAP2β protein knockdown affects location of lamin B and nucleoporins and has effect on assembly of cell nucleus and cell viability

Xenopus LAP2β protein is the single isoform expressed in XTC cells. The protein localizes on heterochromatin clusters both at the nuclear envelope and inside a cell nucleus. The majority of XLAP2β fraction neither colocalizes with TPX2 protein during interphase nor can be immunoprecipitated with XLA...

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Detalles Bibliográficos
Autores principales: Dubińska-Magiera, Magda, Chmielewska, Magdalena, Kozioł, Katarzyna, Machowska, Magdalena, Hutchison, Christopher J., Goldberg, Martin W., Rzepecki, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819936/
https://www.ncbi.nlm.nih.gov/pubmed/26209045
http://dx.doi.org/10.1007/s00709-015-0861-y