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Building a Robust Tumor Profiling Program: Synergy between Next-Generation Sequencing and Targeted Single-Gene Testing

Next-generation sequencing (NGS) is a powerful platform for identifying cancer mutations. Routine clinical adoption of NGS requires optimized quality control metrics to ensure accurate results. To assess the robustness of our clinical NGS pipeline, we analyzed the results of 304 solid tumor and hema...

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Detalles Bibliográficos
Autores principales: Hiemenz, Matthew C., Kadauke, Stephan, Lieberman, David B., Roth, David B., Zhao, Jianhua, Watt, Christopher D., Daber, Robert D., Morrissette, Jennifer J. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820127/
https://www.ncbi.nlm.nih.gov/pubmed/27043212
http://dx.doi.org/10.1371/journal.pone.0152851