HEK293T Cells Are Heterozygous for CCR5 Delta 32 Mutation

C-C chemokine receptor 5 (CCR5) is a receptor for chemokines and a co-receptor for HIV-1 entry into the target CD4+ cells. CCR5 delta 32 deletion is a loss-of-function mutation, resistant to HIV-1 infection. We tried to induce the CCR5 delta 32 mutation harnessing the genome editing technique, CRISP...

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Detalles Bibliográficos
Autores principales: Qi, Chunxia, Jia, Xiaopeng, Lu, Lingling, Ma, Ping, Wei, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820142/
https://www.ncbi.nlm.nih.gov/pubmed/27042825
http://dx.doi.org/10.1371/journal.pone.0152975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820142/
https://www.ncbi.nlm.nih.gov/pubmed/27042825
http://dx.doi.org/10.1371/journal.pone.0152975

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