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An Inducible System for Rapid Degradation of Specific Cellular Proteins Using Proteasome Adaptors

A common way to study protein function is to deplete the protein of interest from cells and observe the response. Traditional methods involve disrupting gene expression but these techniques are only effective against newly synthesized proteins and leave previously existing and stable proteins untouc...

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Detalles Bibliográficos
Autores principales: Wilmington, Shameika R., Matouschek, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820223/
https://www.ncbi.nlm.nih.gov/pubmed/27043013
http://dx.doi.org/10.1371/journal.pone.0152679