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In-Depth Assessment of the Palladium-Catalyzed Fluorination of Five-Membered Heteroaryl Bromides

[Image: see text] A thorough investigation of the challenging Pd-catalyzed fluorination of five-membered heteroaryl bromides is presented. Crystallographic studies and density functional theory (DFT) calculations suggest that the challenging step of this transformation is C–F reductive elimination o...

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Detalles Bibliográficos
Autores principales: Milner, Phillip J., Yang, Yang, Buchwald, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820280/
https://www.ncbi.nlm.nih.gov/pubmed/27056379
http://dx.doi.org/10.1021/acs.organomet.5b00631