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Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study

BACKGROUND: Effective targeted therapy for sepsis requires an understanding of the heterogeneity in the individual host response to infection. We investigated this heterogeneity by defining interindividual variation in the transcriptome of patients with sepsis and related this to outcome and genetic...

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Detalles Bibliográficos
Autores principales: Davenport, Emma E, Burnham, Katie L, Radhakrishnan, Jayachandran, Humburg, Peter, Hutton, Paula, Mills, Tara C, Rautanen, Anna, Gordon, Anthony C, Garrard, Christopher, Hill, Adrian V S, Hinds, Charles J, Knight, Julian C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820667/
https://www.ncbi.nlm.nih.gov/pubmed/26917434
http://dx.doi.org/10.1016/S2213-2600(16)00046-1