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Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study
BACKGROUND: Effective targeted therapy for sepsis requires an understanding of the heterogeneity in the individual host response to infection. We investigated this heterogeneity by defining interindividual variation in the transcriptome of patients with sepsis and related this to outcome and genetic...
Autores principales: | Davenport, Emma E, Burnham, Katie L, Radhakrishnan, Jayachandran, Humburg, Peter, Hutton, Paula, Mills, Tara C, Rautanen, Anna, Gordon, Anthony C, Garrard, Christopher, Hill, Adrian V S, Hinds, Charles J, Knight, Julian C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820667/ https://www.ncbi.nlm.nih.gov/pubmed/26917434 http://dx.doi.org/10.1016/S2213-2600(16)00046-1 |
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