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Integrin α1β1 expression is controlled by c-MYC in colorectal cancer cells

The α1β1 collagen receptor is only present in a few epithelial cell types. In the intestine, it is specifically expressed in proliferating crypt cells. This integrin has been reported to be involved in various cancers where it mediates the downstream activation of the Ras/ERK proliferative pathway....

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Detalles Bibliográficos
Autores principales: Boudjadi, S, Carrier, J C, Groulx, J-F, Beaulieu, J-F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820680/
https://www.ncbi.nlm.nih.gov/pubmed/26096932
http://dx.doi.org/10.1038/onc.2015.231