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Molecular Interactions between Tarantula Toxins and Low-Voltage-Activated Calcium Channels

Few gating-modifier toxins have been reported to target low-voltage-activated (LVA) calcium channels, and the structural basis of toxin sensitivity remains incompletely understood. Studies of voltage-gated potassium (Kv) channels have identified the S3b–S4 “paddle motif,” which moves at the protein-...

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Detalles Bibliográficos
Autores principales: Salari, Autoosa, Vega, Benjamin S., Milescu, Lorin S., Milescu, Mirela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820701/
https://www.ncbi.nlm.nih.gov/pubmed/27045173
http://dx.doi.org/10.1038/srep23894