Epigenetic regulation of NKG2D ligands is involved in exacerbated atherosclerosis development in Sirt6 heterozygous mice

Sirt6 is a member of the class III histone deacetylase family which is associated with aging and longevity. Sirt6 deficient mice show an aging-like phenotype, while male transgenic mice of Sirt6 show increased longevity. Sirt6 acts as a tumor suppressor and deficiency of Sirt6 leads to cardiac hyper...

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Detalles Bibliográficos
Autores principales: Zhang, Zhu-Qin, Ren, Si-Chong, Tan, Ying, Li, Zuo-Zhi, Tang, Xiaoqiang, Wang, Ting-Ting, Hao, De-Long, Zhao, Xiang, Chen, Hou-Zao, Liu, De-Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820703/
https://www.ncbi.nlm.nih.gov/pubmed/27045575
http://dx.doi.org/10.1038/srep23912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820703/
https://www.ncbi.nlm.nih.gov/pubmed/27045575
http://dx.doi.org/10.1038/srep23912

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